Arimidex (Anastrozole) 1mg. Arimidex acts by suppressing the levels of estrogen in the body and thus reduces the growth of breast cancer.
Arimidex (Anastrozole) 1mg
Arimidex (anastrozole) is a non-steroidal drug which is used to treat breast cancer. It has been thoroughly studied in women with breast cancer between the 5th-8th decades of life.
There are some breast cancers which are dependent on estrogen for their growth. Arimidex acts by suppressing the levels of estrogen in the body and thus reduces the growth of breast cancer.
The drug is first line treatment in post menopausal women with early breast cancer or in those with advanced breast cancer despite taking tamoxifen.
Arimidex is often combined with other drugs to treat breast cancer in post menopausal women. The drug has been used to treat early or advanced breast cancer in women all cultures and races.
Arimidex is not a large molecule but still it is not very soluble in water. Because of its organic structure, it is more soluble in alcohols like methanol, acetone, ethanol and acetonitrile.
When taken orally, Arimidex enters the liver where more than 90% is broken down into inactive metabolites. In individuals who have mild liver disease, cirrhosis or have alcoholic liver problems, the drug is safe.
However, in individuals with severe liver disease, the drug does have the potential to cause side effects.
Because Arimidex is not excreted in the urine, people with kidney impairment can take the drug without any dosage changes. Further, the drug dosage does not have to be altered in the elderly individuals either.
Arimidex in the US is administered by physicians who specialize in the treatment of cancer. Arimidex is sold as a pill containing 1 mg of anastrozole.
The formulation of the pill also contains other inactive chemicals like lactose, magnesium sterate, polyethylene glycol, sodium starch glycolate and titanium dioxide. These ingredients make the active anastrozole more soluble in water, and make it easier to prepare as a pill.
Arimidex is taken orally everyday as a 1-mg tablet. All the patients with advanced breast cancer who have been prescribed the drug take it until a response in the tumour is seen.
For those patients who take Arimidex as part of adjuvant (a substance that helps and enhances the pharmacological effect of a drug) therapy, the exact duration of the treatment remains unknown but most experts recommend that women take it for 5 years.
28 x 1mg Tablets